Product Name :
mGluR6 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CSNB1B antibody DKFZp686H1993 antibody GluR6 antibody Glutamate receptor metabotropic 6 antibody GPRC1F antibody Grm6 antibody GRM6_HUMAN antibody Metabotropic glutamate receptor 6 antibody mGlu6 antibody mGluR6 antibody
Function :
mGluR6 is specifically expressed in the retina, in a subtype of bipolar cells that depolarize in response to light, known as ON bipolar cells. These cells form synapses with photoreceptor cells, and detect the neurotransmitter glutamate via a GPCR signal transduction cascade. The glutamate receptor mGluR6 is located post-synaptically at the tips of the bipolar cell dendrites, and is responsible for initiating a signaling cascade that ultimately controls gating of the TRPM1 channel. In human patients, mutations in the GRM6 gene are associated with congenital stationary night blindness.Ribavirin site
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human mGluR6 aa 820-877.6-Bromo-2-fluoro-3-methoxybenzoic acid site
Species reactivity:
Human
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3071255
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33739385 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 95 kDa
Positive control :
HepG2 cell lysates, SHSY5Y.