Product Name :
XRCC4 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
DNA double strand break repair and V(D)J recombination protein XRCC4 antibody DNA repair protein XRCC4 antibody SSMED antibody X ray repair complementing defective repair in Chinese hamster cells 4 antibody X ray repair cross complementing 4 antibody X ray repair cross complementing protein 4 antibody X-ray repair cross-complementing protein 4 antibody XRCC 4 antibody XRCC4 antibody XRCC4_HUMAN antibody
Function :
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human XRCC4 151-260/336
Species reactivity:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.Formula of RuPhos Pd G4 Avoid repeated freeze/thaw cycles.Buy8-Chloro-2-methyl-1,5-naphthyridine The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33567813 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
38/60 KDa
Positive control :
Widely expressed.